By Alkire R.S., Kolb D.M., Lipkowski J. (eds.)
Content material: Preface AMPEROMETRIC BIOSENSORS advent standards for "Good" Biosensor examine Defining a typical for Characterizing Biosensor Performances luck tales in Biosensor study end IMAGING OF unmarried BIOMOLECULES through SCANNING TUNNELING MICROSCOPY creation Interfacial Electron move in Molecular and Protein movie Voltammetry Theoretical Notions in Bioelectrochemistry in the direction of the Single-Molecule point In Situ Imaging of Bio-related Molecules and Linker Molecules for Protein Voltammetry with Single-Molecule and Sub-molecular solution Imaging of Intermediate-Size organic constructions: Lipid Membranes and Insulin Interfacial Electrochemistry and In Situ Imaging of Redox Metalloproteins and Metalloenzymes on the Single-Molecule point a few Concluding Observations and Outlooks functions OF NEUTRON REFLECTIVITY IN BIOELECTROCHEMISTRY advent Theoretical features of Neutron Scattering Experimental facets chosen Examples precis and destiny elements version LIPID BILAYERS AT ELECTRODE SURFACES creation Biomimetic Membranes: Scope and specifications Electrochemical Impedance Spectroscopy Formation of Lipid movies in Biomimetic Membranes a number of forms of Biomimetic Membranes Conclusions ENZYMATIC gasoline CELLS advent Bioanodes for Glucose Oxidation Biocathodes Assembled Biofuel Cells Conclusions and destiny Outlook RAMAN SPECTROSCOPY OF BIOMOLECULES AT ELECTRODE SURFACES creation Raman Spectroscopy SERS and Surface-Enhanced Resonant Raman Spectroscopy comparability of SE(R)RS and Fluorescence for organic reviews Surfaces for SERS Plasmonic Surfaces SERS Surfaces for Electrochemistry Tip-Enhanced Raman Spectroscopy SE(R)RS of Biomolecules end MEMBRANE ELECTROPORATION IN excessive electrical FIELDS creation Electrodeformation and Electroporation of Membranes within the Fluid section reaction of Gel-Phase Membranes results of Membrane Inclusions and Media at the reaction and balance of Fluid Vesicles in electrical Fields program of Vesicle Electroporation Conclusions and Outlook ELECTROPORATION FOR clinical USE IN DRUG AND GENE ELECTROTRANSFER creation a listing of Definitions How We comprehend Permeabilization on the mobile and Tissue point uncomplicated facets of Electroporation which are of specific significance for scientific Use the way to convey electrical Pulses in sufferer therapy therapy and Post-treatment administration medical effects with Electrochemotherapy Use in inner Organs Gene Electrotransfer Conclusions
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Additional info for Bioelectrochemistry : fundamentals, applications and recent developments
Due to the limitations for direct ET as derived from Marcus theory, these observations are most likely not caused by a true direct ET process but alternative explanations have to be considered despite the observed and repeatedly obtained effects. Alternatively, the ET distance may be decreased by the formation of enzyme–nanoparticle hybrids in which the nanoparticle penetrates into the protein shell . However, in these cases the catalytic current for glucose oxidation is often obtained at high overpotentials.
The modiﬁcation of biomolecules with nanomaterials or coupling of biomolecules and nanomaterials is the third category of approach towards nanobiosensors. Of course the lines between these approaches are blurred and some sensor designs may draw from more than one of these concepts. 1 Modiﬁcation of Macroscopic Transducers with Nanomaterials There is an enormous variety of nanomaterials that can potentially be employed in biosensor architectures. The most prominent among them are metal nanoparticles , quantum dots , and carbon nanotubes [309–311].
The modiﬁcation of a (macroscopic) transducer with nanomaterials is the ﬁrst of these approaches. In electrochemical biosensors, this would translate into large electrodes modiﬁed with nanomaterials. The second approach is the miniaturization of the transducer, namely the use of nanoelectrodes  or other miniaturized circuitry of nanometric dimensions. The modiﬁcation of biomolecules with nanomaterials or coupling of biomolecules and nanomaterials is the third category of approach towards nanobiosensors.