By Terry W. Campbell, Krystan Grant
Clinical instances in Avian and unique Animal Hematology and Cytology demonstrates tips on how to use hemic cytology and cytodiagnosis as a part of the evaluate of an unique animal sufferer, taking the reader via approximately a hundred real medical circumstances. With a spotlight on cytological interpretation, the hands-on, functional process enables studying, educating, and comprehension. Well illustrated all through, Clinical circumstances in Avian and unique Animal Hematology and Cytology is a worthy advisor for exotics veterinarians, zoo and aquarium veterinarians, and veterinary hematologists.
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Once specificity is determined, antigen-negative PRBCs can be provided by the blood bank, though this can significantly delay a transfusion. A type and crossmatch order should be submitted if blood transfusion is required within the subsequent 12 hours. Patients are typed for ABO and Rh antigens, and an antibody screen is performed. However, with this order, unlike the type and screen, the appropriate blood product is crossmatched with the patient’s serum prior to being issued (Brecher 2002). All blood banks perform a crossmatch procedure before issuing any WB or PRBC component, except in an emergency.
Based on the fact that granulocyte concentrates contain large numbers of lymphocytes, there is consensus that all granulocyte transfusions should be irradiated to prevent TA-GVHD. Additionally, for granulocyte transfusions to neonates, donors are usually selected to be CMV seronegative and must be ABOgroup compatible with the infant. Additional manipulation of granulocytes, such as splitting the product, may in fact be detrimental to the constituents of the product. RECORD KEEPING FOR COMPONENT PREPARATION Current good manufacturing practice (cGMP) regulations require that records be maintained for all aspects of component preparation (Brecher 2002; Gorlin 2002).
1991). qxd 12/19/05 4:12 PM Page 30 30 Josephson and Hillyer 20 mL/kg with a maximum of approximately 2 units to be infused over 2 to 4 hours depending on the patient’s disease process and healthcare constraints. The choice of PRBCs (preservative solution) for these ages is much less critical due to the child’s increased blood and plasma volume. tions, nor do they protect against the development of TA-GVHD (Hume and Preiksaitis 1999). All three of these special processes are discussed in greater detail in Section III, Chapters 7, 9, and 10.