By Alan List
An evaluation of prognosis and present administration of myelodysplastic syndromes.
- studies the functionality of the pharmacological remedies presently to be had and analyses the opportunity of new treatments
- prime quality medical pictures and figures to augment descriptions and increase reader comprehension
- precious reference textual content for healthcare execs wanting to understand extra approximately myelodysplastic syndromes
Read or Download Clinician’s Manual on Myelodysplastic Syndromes PDF
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Extra resources for Clinician’s Manual on Myelodysplastic Syndromes
Int J Hematol 2002; 75:289–297. 21. Hirai H. Molecular mechanisms of myelodysplastic syndrome. Jpn J Clin Oncol 2003; 33:153–160. 22. Davis RE, Greenberg PL. Bcl-2 expression by myeloid precursors in myelodysplastic syndromes: relation to disease progression. Leuk Res 1998; 22:767–777. 23. Quesnel B, Guillerm G, Vereecque R, et al. Methylation of the p15INK4b gene in myelodysplasic syndromes is frequent and acquired during disease progression. Blood 1998; 91:2985–2990. 24. Jansen AJG, Essink-Bot ML, Beckers EAM, et al.
Remission) after 24 weeks of treatment and 28% achieved a partial response. Lenalidomide was well tolerated with manageable myelosuppressive effects . Moderate-to-severe neutropenia and thrombocytopenia occurred in 55% and 44% of patients, respectively. There were 11 deaths during the extended treatment follow-up, including three possible treatment-related deaths due to neutropenic-associated infection that occurred early after study activation owing to insufficient frequency of laboratory monitoring.
Shadduck RK, Latsko JM, Rossetti JM, et al. Recent advances in myelodysplastic syndromes. Exper Hematol 2007; 35:137–143. 55. Stasi R, Abruzzese E, Lanzetta G, et al. Darbepoetin alfa for the treatment of anemic patients with low- and intermediate-1-risk myelodysplastic syndromes. Ann Oncol 2005; 16:1921–1927. 56. Giraldo P, Nomdedeu B, Loscertales J, et al. Darbepoetin for the treatment of anemia in patients with myelodysplastic syndromes. Cancer 2006; 107:2807–2816. 57. Hellström-Lindberg E, Negrin R, Stein R, et al.