By Michael Laposata MD PhD
The Diagnostic criteria of Care sequence provides universal blunders linked to diagnoses in scientific pathology, utilizing case examples to demonstrate powerful research in response to present proof and criteria. as well as being useful diagnostic publications, each one quantity demonstrates using caliber coverage and the function of the pathologist in making sure caliber and sufferer security.
Coagulation Disorders is designed to teach medical pathologists, lab managers, scientific technologists, and citizens find out how to keep away from universal blunders in attempt choice and end result interpretation in diagnostic coagulation. using a case-based process, each one bankruptcy contains a concise evaluation of an important analysis, with a number of illustrative instances, after which a listing of suggested criteria of care pertinent to the matter.
simply because it is vital for the practitioner within the prognosis of bleeding and thrombotic problems to grasp the precise plan of action to set up a prognosis or to correctly deal with a sufferer, it's both necessary to additionally understand what to not do. keeping off the blunders is a severe first step to optimizing sufferer final result and maximizing sufferer security.
positive factors of Coagulation problems contain:
- An emphasis on settling on verified, evidence-based criteria in coagulation trying out
- Actual case illustrations of usually obvious error in addition to the results of these blunders on sufferer final result and laboratory administration
- Examples of blunders which compromise sufferer defense throughout all significant parts of laboratory drugs
- Pocket-sized for portability
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The Diagnostic criteria of Care sequence provides universal blunders linked to diagnoses in scientific pathology, utilizing case examples to demonstrate potent research in keeping with present proof and criteria. every one quantity demonstrates using caliber insurance and the function of the pathologist in making sure caliber and sufferer safeguard.
Additional resources for Coagulation Disorders: Diagnostic Standards of Care
The platelet count in patients receiving low molecular weight heparin, for several compelling reasons described in this chapter, is monitored less often than it is for hospitalized patients receiving unfractionated heparin. 24 3. Patients Being Treated with Low Molecular Weight Heparin TEST ORDERING MISTAKES Ordering a PTT assay to monitor anticoagulation with low molecular weight heparin instead of the anti-factor Xa assay. Low molecular weight heparin treatment, even at therapeutic doses, results in only a mild prolongation of the PTT in most cases.
Evaluation for Heparin-induced Thrombocytopenia HIT-associated thromboses include deep vein thrombosis, pulmonary embolism, stroke, peripheral artery thrombosis and massive thrombosis with death. These poor clinical outcomes have in recent years resulted in a high vigilance state among physicians for this condition. There has been increased legal action against physicians who fail to recognize, demonstrate, and appropriately treat patients with HIT. The major challenge in this condition is that many patients will develop the antibody associated with HIT, which recognizes the heparin–platelet factor 4 complex, but they will not go on to develop thrombocytopenia or subsequently, thrombosis.
Test Ordering Mistakes 45 Explanation and Consequences This case illustrates that argatroban can still be used in patients with liver disease with appropriate dose adjustments. Fortunately, the dose of argatroban was promptly adjusted to reduce the likelihood of major bleeding. Argatroban produces significant interference with the INR. Therefore, in patients being treated with argatroban and warfarin at the same time, with the intention to discontinue argatroban when a therapeutic effect of warfarin is achieved, the INR cannot be used to determine the warfarin effect.