Download Colorectal Cancer: Special Issue: Digestive Diseases 2007 by C. Dervenis, E. Xynos PDF

By C. Dervenis, E. Xynos

Over the past 3 a long time, loads of development has been made concerning the genetics, typical historical past, analysis, actual staging and healing modalities of rectal melanoma. This improvement has ended in a considerable development in survival and native recurrence charges, exceeding these accomplished for colon melanoma. although surgical procedure continues to be the cornerstone of the therapy of rectal melanoma, learn has persevered to set up new guidance for a multi-modality remedy leading to even extra greater recurrence and survival charges, and caliber of life.This booklet positive aspects stories on present wisdom and remedy traits, starting from neo-adjuvant chemoradiation and radiotherapy to preoperative staging and the benefits and demanding situations of a laparoscopic method. additionally, in a evaluation of the molecular organic alterations characterizing colorectal melanoma, the potential implementations of genetic experiences in screening and follow-up are mentioned. eventually, the difficulty additionally comprises unique articles targeting numerous facets of the administration of sufferers struggling with the illness.

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Extra resources for Colorectal Cancer: Special Issue: Digestive Diseases 2007

Example text

3 Selke B, Durand I, Marissal J, Chevalier D, Lebrun T: Cost of colorectal cancer in France in 1999 (in French). Gastroenterol Clin Biol 2003;27:22–27. 4 Dickersin K, Scherer R, Lefebvre C: Identifying relevant studies for systematic reviews. BMJ 1994;309:1286–1291. 5 Tumber M, Dickersin K: Publication of clinical trials: accountability and accessibility. J Int Med 2004;256:271–283. 6 Bohm B, Schwenk W, Muller J: Long-term results after laparoscopic resection of colorectal carcinoma (in German).

29] also looked at QOL as related to longterm complications and survival rate (n = 391). Overall QOL was significantly better in the LCR during the first 12 months after surgery, associated with a lower incidence of long-term complications, whereas at 24 months LCR patients reported a significant advantage only in social functioning. In the CLASICC multicenter clinical trial [34], EORTC QLQ-C30 scores for global QOL and functional scales showed that there was no significant difference at 2 weeks and 3 months.

3 Selke B, Durand I, Marissal J, Chevalier D, Lebrun T: Cost of colorectal cancer in France in 1999 (in French). Gastroenterol Clin Biol 2003;27:22–27. 4 Dickersin K, Scherer R, Lefebvre C: Identifying relevant studies for systematic reviews. BMJ 1994;309:1286–1291. 5 Tumber M, Dickersin K: Publication of clinical trials: accountability and accessibility. J Int Med 2004;256:271–283. 6 Bohm B, Schwenk W, Muller J: Long-term results after laparoscopic resection of colorectal carcinoma (in German).

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